The San Vicente Stakes is an American thoroughbred horse race run annually at Santa Anita Park. A Grade III event, the race is open to three-year-old horses willing to race seven furlongs on the dirt and carries a purse of $150,000.

Inaugurated in 1935 as the San Vicente Handicap, it was open to older horses until 1937. The race was run as a handicap event from 1935 until 1941, 1945 through 1948, 1956 through 1958, and 1960 through 1965. There was no race held from 1942 until 1944, 1949 until 1951, and again in 1970. In 1952 and 1953 the race was restricted to colts and geldings. Since inception, it has been run at various distances.

Louis B. Mayer's U.S. Racing Hall of Fame filly, Busher, won this race against males in 1945. The filly, Hubble Bubble, won in 1947. In 2009 Evita Argentina became the third filly to win this race in 68 runnings.