The Arcadia Handicap is an American Thoroughbred horse race typically run in early April at Santa Anita Park in Arcadia, California. Open to horses four years of age and older, it is raced on turf over a distance of one mile. A Grade II race, it currently offers a purse of $150,000.

Inaugurated in 1988 as the El Rincon Handicap, it was renamed the Arcadia Handicap in 2001 after the original Arcadia Handicap had been renamed the Frank E. Kilroe Mile Handicap. Two Lea won this race in 1949. From 1998 through 2004, the race was run at a distance of 1 1/8 miles.